ZIACOM carried out a rigorous study on the surface treatment of its implants, Osseonova now Titansure. For this purpose, FISEVI, Fundación Pública Andaluza para la Gestión de la Investigación en Salud de Sevilla, carried out an exhaustive analysis of the Osseonova surface. The project was structured in three main areas: surface characterisation, cellular growth on the same surface and analysis of the osseointegration of ZIACOM implants on animal model.
This research, conducted by Dr. Daniel Torres Lagares (Doctor of Dentistry, Master in Oral Surgery and Clinical Trials) has been prolonged for more than a year and today, we are pleased to publish a satisfactory results of the Osseonova surface clinical behavior.
During the first part of this project, a “descriptive study of surface treatment for Osseonova dental implants” was carried out. The aim of this investigation was to evaluate the surface roughness and surface composition of the Osseonova treatment. In order to achieve the targets, scanning electron microscopy (SEM) and other analysis methods were used to typify the composition and structure of the surface. As a conclusion, it was determined that the composition of ZIACOM implants treated and not treated with Osseonova are similar, even though the implementation of the treatment resulted in a rougher and more suitable surface for osseointegration of dental implants.
In the second part of the study, the analysis of “cell growth on the Osseonova surface” was carried out. The aim was to evaluate the suitability of the ZIACOM implant surface compared to the Zimmer and Biohorizons implant surfaces through cell cultures. The results obtained on the percentage of cell viability between the different implants were very similar, ranging from 100% to 100% at 6 hours, from 50% to 52% at 24 hours and from 270% to 295% at 48 hours (DNES). The mitochondrial activity percentage moved in the range of 93.85% to 97.74% for the implants studied, compared to 95.35% detected in the control (DNES). This translates into an adequate cellular prophylaxis to favour the osseointegration process and leads to the success of the treatment.
In the last part of the study, the “osseointegration of ZIACOM implants in animal model” was carried out. The purpose of this project was to evaluate the osseointegration and behaviour of ZIACOM dental implants, compared to Zimmer and Biohorizons implants, placed on an animal model. The implants were placed in New Zeland rabbit tibias and a radiological and histomorphometric analysis was performed 6 weeks after implantation. The suitability of the Osseonova surface treatment for osseointegration of ZIACOM implants is highlighted by the obtained results, with significant advantages compared to other samples.